Education:

09/2019-11/2020 Visiting Scholar in University of California Riverside College of chemistry and chemical engineering

6/2018 PhD of Analytical Chemistry, College of chemistry and chemical engineering, State Key Laboratory of Chemo/Biosensing and Chemo-metrics, Hunan University, Changsha

10/2015-6/2018 Doctoral student, Department of Chemistry, Tsinghua University, Beijing

09/2000-06/2003 Master of Analytical Chemistry, College of chemistry and chemical engineering, State Key Laboratory of Chemo/Biosensing and Chemo-metrics, Hunan University, Changsha

6/1995 Bachelor of Chemistry, College of Chemistry, Hunan university of Humanities, Science and Technology.

Academic Appointments:

9/2003-Present Department of Pharmacy, University of South China, Hengyang, Hunan Province, China

Publications in recent years:

(1)Kaiyue Wu, Miaojia Chen, Xiaoyu Peng, Yang Li, Guotao Tang, Junmei Peng, Xuan Cao*.Recent progress of research on the benzimidazole PARP-1 inhibitors, Mini-Reviews in Medicinal Chemistry. 2022 (accepted and to be published)(IF=?)

(2)Kaiyue Wu, Xiaoyu Peng, Miaojia Chen, Yang Li, Guotao Tang, Junmei Peng, Yuanyuan Peng, Xuan Cao*.Recent progress of research on anti-tumor agents using benzimidazole as the structure unit, Chem. Biol. Drug Des. 2022, 00:1-22. DOI:10.1111/cbdd.14022 (IF=?)

(3) Miaojia Chen, Honglin Huang, Kaiyue Wu, Guotao Tang, Junmei Peng, Xuan Cao*. Synthesis and evaluation of2-(4-[4-acetylpiperazine-1-carbonyl] phenyl)-1H-benzo[d]imidazole-4-carboxamide derivatives as potential PARP-1 inhibitors and preliminary study on structure-activity relationship, Drug Development Research, 2021, 83(8): 1-9. DOI:10.1002/ddr.21843 (IF=4.360)

(4) Jinmei Qiu, Changfeng Qin, Shengen Wu, Tongying Ji, Guotao Tang, Xiaoyong Lei, Xuan Cao*, Zhizhong Xie*.A novel salvianolic acid A analog with resveratrol structure and its antioxidant activities in vitro and invivo，Drug Development Research, 2020, 82(6): 108-114. DOI:10.1002 /ddr.21734 (IF=4.360)

(5) Jingjing Feng^#, Xuan Cao^# (co-author), Qi Pan, Yan He.* Direct observation of Single Plasmonic Metal Nanoparticle Reaction in Microcolumn with Chromatic-Aberration-Free Laser Light-Sheet Scattering Imaging. Electrophoresis, 2019, 40(13):1747-1753 DOI: 10.1002/elps.201900071 (IF=3.08)

(6)Xuan Cao^#, Gang Lei, Jing Jing Feng, Qi Pan, Yan He.* A Novel Color Modulation Analysis Strategy through Tunable Multiband Laser for Nanoparticle Identification and Evaluation, Anal. Chem., 2018, 90(4):2501-2507. DOI:10.1021/acs.analchem. 7b03636 (IF=6.042)

(7) Xuan Cao, Jingjing Feng, Qi Pan, Bin Xiong, Yan He,* and Edward S. Yeung. Direct Imaging of Single Plasmonic Metal Nanoparticles inCapillary with Laser Light-Sheet Scattering Imaging. Anal. Chem., 2017. 89(2):2692-2697. DOI:10.1021 /acs.analchem.6b03844 (IF=6.320)

(8) Xiaodong Cheng, Xuan Cao, Bin Xiong, Yan He,* and Edward S. Yeung. Background-free three-dimensional selective imaging of anisotropic plasmonic nanoparticles. Nano Res., 2017. 10(4):1423-1433.

DOI: 10.1007/s12274-017-1524-4 (IF=7.354)

(9)Lan Peng,Xuan Cao, Bin Xiong,* Yan He* and Edward S. Yeung. A novel scattering switch-on detection technique for target-induced plasmon-coupling based sensing by single-particle optical anisotropy imaging. Chem Commun., 2016, 52(2):7616-7619. DOI: 10.1039/ c6cc02536f (IF=6.567)

Research Interest

Pharmaceutical chemistry

1) Design and totally synthesize potential PARP1 inhibitor

2) Natural anti-tumor agents such as Salvianolic Acid A analogs.